Here is a small script I use to clear out the junk files (temp, internet etc) off all local profiles.
IF "%OS%"=="" GOTO WIN9X
@REM - FIND "DOCUMENTS AND SETTINGS" FOLDER:
%SYSTEMDRIVE%
CD %USERPROFILE%\..
FOR /D %%F IN (*.*) DO DEL /F/S/Q "%%F\LOCAL SETTINGS\TEMP\*.*"
FOR /D %%F IN (*.*) DO DEL /F/S/Q "%%F\LOCAL SETTINGS\TEMPORARY INTERNET FILES\*.*"
FOR /D %%F IN (*.*) DO DEL /F/S/Q "%%F\COOKIES\*.*"
DEL /F/S/Q %WINDIR%\TEMP\*.*
DEL /F/S/Q %WINDIR%\*.TMP
GOTO END
:WIN9X
REM - WIN9X systems are currently not supported.
:END
Takes a while when first run, but daily it's fantastic.