ContributionsMost RecentMost LikesSolutionsRe: Local keyboard and mouse do not respond I did - The issue is specific to when I am swapping between my keyboard, and mouse - I also thought it might be my mouse configurations, but that did not help either. At quite a loss. Re: Local keyboard and mouse do not respond I am having a similar issue. My keyboard seems to simply disconcect when I work with my mouse. I have to minimize and reopen Logmein to get it going again, and sometimes it still doesn't boot back up. This is aggravating when it comes to emails, but I spend most of my time in adobe programs (very mouse/keyboard heavy programs) and am basically unable to get my work done.