I have Hamachi running on a Server 2012 R2. Late last night Hamachi did an automatic update to v220.127.116.118. At the same time Event Viewer started logging errors because the static TCP/IPv4 address on the server had been removed. It appears that the Hamachi update caused the Network Bridge to be reset to defaults.
Luckily I was able to put the static IP back in along with the gateway and DNS and it is functioning correctly now.
I am posting this to find out if anyone else has had the same experience and also to help anyone who may have the same issue.